Tetramethylguanidine/TMG

 

Other name: 1,1,3,3-Tetramethylguanidine(TMG)

CAS No.: 80-70-6

Molecular formula: C5H13N3

Molecular weight: 115.18

EINECS No.: 201-302-7

Melting point: -30°C

Boiling point: 162-163 °C (lit.)

Density: 0.916 g/mL at 20 °C (lit.)

Storage conditions: Store below +30°C

Form: Liquid

PH value: 12.7 (10g/l, H2O, 25℃)

Water solubility: miscible

Sensitivity: Air Sensitive

Stability: Stable. Combustible. Incompatible with strong oxidizing agents, mineral and organic acids, carbon dioxide. Air-sensitive.

 

Use:

In organic synthesis, 1,1,3,3-tetramethylguanidine is used as a strong, non-nucleophilic base. 1,1,3,3-Tetramethylguanidine is an efficient and selective catalyst for the benzoylation of alcohols.

It is mainly used as a catalyst for polyurethane foam, and also used for level dyeing of nylon (nylon), wool and other proteins.

 

Physical and chemical properties:

Tetramethylguanidine is a colorless oily liquid with a boiling point of 160-162°C, a density of 0.918, and a refractive index of 1.4692. It is an organic strong base, soluble in toluene, cyclohexanone, ethanol, etc., and also soluble in water. In alkaline aqueous solution It is easily hydrolyzed into tetramethylurea, which is corrosive, and is usually packed in galvanized iron drums.

 

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