HMDS/Hexamethyldisilazane

Other names: HMDS; Hexamethyldisilazane; DYNASYLAN HMDS; Bis(trimethylsilyl)amine; 1,1,1-Trimethyl-N-(trimethylsilyl)silanamine

Molecular formula: C6H19NSi2

CAS No.: 999-97-3

Melting point: -78℃

Boiling point: 125℃

Density: 0.774

Properties: Colorless transparent liquid, non-toxic, slightly amine smell.

Solubility: soluble in organic solvents

Storage conditions: 2-8°C

Sensitivity: Moisture Sensitive

Water solubility: It will be hydrolyzed rapidly to form trimethylsilanol and hexamethyldisiloxane in contact with air

Category: Flammable Liquids

Toxicity classification: poisoning

Flammability hazard characteristics: flammable in case of open flame, high temperature and oxidant; decomposes toxic silicide gas in case of water; produces toxic nitrogen oxide smoke when burned

 

Use

 

Industry: used in the production of rubber and medicine. This product is a tail reducer for reducing the adsorption activity on the surface of gas chromatography carrier. It is a pharmaceutical intermediate of amikacin and a protective agent for hydroxyl and amino groups. Specialty Organic Synthesis. A silylating reagent, which can be used in the production of Amikacin.

Medicine: It can be used in special organic synthesis. Silylation in the synthesis of amikacin, penicillin, cephalosporin, fluorouracil and various penicillin derivatives.

Mining industry: It can be used for surface treatment of diatomite, white carbon black, titanium and other powders. Its mechanism of action is condensation of silicon-nitrogen bonds and silicon hydroxyl groups.

Used as an adhesion aid for photoresists in the semiconductor industry.

In organosilazane chemistry, it can be used for chlorine exchange with chlorosilane monomers to obtain polysilazanes. This method has a huge advantage in synthesis than the direct ammonia method.

 

Note: This substance is a simple silazane monomer. Plays an important role in silicon nitride chemistry. The characteristic of silazane is that it is easy to hydrolyze, and it is easy to react with hydroxyl to eliminate hydroxyl. Widely used as a surface treatment to enhance adhesion.

 

 

PIC: Pepper Wang
Email: km12@kmchem.com
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